side effects of covid vaccine pfizer vs moderna

Once a vial is opened and prepared for injection, it can be kept at room temperature for up to 2 hours. Unlike the two mRNA vaccines, the J&J vaccine can be refrigerated rather than frozen because it’s more stable at higher temperatures. This helps prevent you from becoming sick with COVID-19. As in the mRNA vaccines, antibodies and immune cells that specifically recognize the spike protein are generated.It then produces an immune response to help fight against the protein. Your immune system notices the spike protein on the surface of the cell and recognizes it as a foreign substance.Once the spike protein is made, it’s displayed on the surface of the cell.Your cells use the information from the adenovirus’s DNA to make spike protein.An adenovirus’s genetic material cannot change or interact with your DNA in any way. Adenoviruses cannot integrate into your DNA. When the vaccine is injected, the adenovirus enters into the surrounding cells.Once the vaccine delivers the adenovirus vector into a host cell, the vector is broken down and the adenovirus cannot cause any harm in the body. The J&J vaccine uses an adenovirus vector, which is a modified inactivated adenovirus (a type of virus) that’s designed not to cause disease in people. Unlike the Pfizer-BioNTech and Moderna vaccines, the J&J vaccine can be given as a single dose. You may see the Johnson & Johnson (J&J) vaccine referred to as JNJ-78436735 or in scientific papers. Once a vial is opened and prepared for an injection, it’s stable at room temperature for up to 12 hours. Similar to the Pfizer-BioNTech vaccine, the Moderna vaccine must also be stored at very cold temperatures, between -58☏ (-50☌) and 5☏ (-15☌). The Moderna vaccine also uses mRNA technology that uses the same mechanism as the Pfizer-BioNTech vaccine to build immunity to the coronavirus spike protein. Like the Pfizer-BioNTech vaccine, the Moderna vaccine is given in two doses spaced 28 days (4 weeks) apart. You may see the Moderna vaccine called mRNA-1273 in scientific papers. Once diluted and prepared for an injection, it can remain at room temperature for up to 6 hours before it becomes unusable. The Pfizer-BioNTech vaccine must be stored at ultra-cold temperatures between -112☏ (-80☌) and -76☏ (-60☌) to keep the mRNA molecule in the vaccine stable. Your immune system can now help protect you from getting sick with COVID-19 because it’s been “trained” to fight against infections caused by exposure to this coronavirus in the future. Your body has now built an immune response to the specific spike protein on the surface of the coronavirus.New antibodies and immune cells that recognize this specific spike protein are produced as your body develops your immune response.

Immune cells in your body recognize the spike protein as a foreign substance and start building an immune response to it.

The cell then displays the spike protein on its surface.When this process is complete, the mRNA is destroyed. The cell uses the information provided by the mRNA to produce the spike protein.Typically, the coronavirus uses the spike protein to bind to other cells and enter them. MRNA provides instructions to the cell for making the spike protein that’s found on the surface of the coronavirus.

It cannot interact with the DNA contained in the nucleus. Once inside a cell, mRNA stays outside the nucleus of the cell.

When the vaccine is injected, surrounding cells take up the mRNA contained in the vaccine.

The Pfizer-BioNTech vaccine uses mRNA technology, which develops immunity using the following process: It’s given in two doses spaced 21 days (3 weeks) apart. The Pfizer-BioNTech vaccine is also called BNT162b2 in the scientific literature and Comirnaty in some countries. Share on Pinterest Design by Maya Chastain Pfizer-BioNTech

Side effects of covid vaccine pfizer vs moderna